Drug Discovery World

 

Almac & Queens Belfast ‘oncology hub’
Mar 2010

Almac, an international drug development organisation, today opens a high-level, invitation only, Washington DC event – ‘From Science to Society: A Northern Ireland Showcase in Cancer Genomics and Personalized Medicine’ – highlighting the capabilities and exceptional work of Northern Ireland’s established ‘oncology hub’. more...

Ambry Genetics & RainDance Partnership
Mar 2010

Ambry Genetics and RainDance Technologies today jointly announced at the Annual CHI Next Generation Sequencing Conference in San Diego, CA their partnership utilizing the RDT 1000 for sequence enrichment and resequencing validation. more...

Omega-3 Protects Against Bowel Polyps
Mar 2010

A new preparation of an omega-3 polyunsaturated fatty acid found naturally in fish, offers hope for thousands of patients at risk of developing an inherited form of bowel cancer, a new study shows. more...

Guide to Automated Barcode Labeling
Mar 2010

Agilent Automation Solutions has produced a new reference guide for life scientists tasked with labeling microplates, who wish to become more familiar with the fundamentals of automated laboratory barcode labeling. more...

Sophion’s QPatch Expands Program
Mar 2010

Sophion Bioscience, Inc. announces the installation of a QPatch system at the Johns Hopkins Ion Channel Center (JHICC) in Baltimore, MD, the premier academic screening center dedicated to high throughput screens and bioactive lead discovery of drugable ion channel targets. more...

Trophos Completes Patient Enrolment
Mar 2010

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for indications with under-served needs in neurology and cardiology, announced today the completion of patient enrolment with over 500 patients recruited into the pivotal phase 3 efficacy study of olesoxime in Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease). more...

Olink Genomics Expands
Mar 2010

Uppsala‐based genomics company, has recruited Fredrik Dahl as company CTO. Dr. Fredrik Dahl will lead the company R&D efforts, with focus on developing the Selector Technology™ and related products. Fredrik Dahl has a track record in inventing, developing, and transferring molecular biology concepts into production scale products. more...

Forbion Leads $12 Million Financing
Mar 2010

Forbion Capital Partners today announces that it has led the Series C investment of Promedior with a syndicate of leading life science investors. more...

Indian Companies Look To Partner UK
Mar 2010

Leading Indian stem cell companies are in the UK this week to seek top tips on how to build links with the UK stem cell sector. Beginning in London, the firms will go on a whistle-stop tour to Cambridge and Edinburgh with UK Trade & Investment (UKTI). more...

Tests Provide Hope For Stomach Cancer
Mar 2010

Dako announced today that two of its products have obtained a CE-mark as diagnostic tests for selecting patients with metastatic stomach (gastric) cancer who may benefit from Herceptin(TM) treatment. Dako's HercepTest(TM) and HER2 FISH pharmDx(TM) enable physicians to identify the unique group of cancer patients that might benefit from the drug. more...

Sigma Further Expands In Vivo Biology
Mar 2010

Sigma-Aldrich today announced it has signed an agreement to acquire Ace Animals Inc., a Berks County, PA.-based provider of high quality research rodents to the biomedical industry. more...

Seegene Breaks PCR Technique Barriers
Mar 2010

Seegene, Inc., a leader in multi-pathogen diagnostic testing, today unveiled a break-through technology called READ (Seegene Real Amplicon Detection) that marks a significant departure with current polymerase chain reaction (PCR) techniques that will enable an entirely new class of powerful molecular diagnostic tests with greater precision. more...

Boston Scientific 1000th Latitude Patient
Mar 2010

Boston Scientific Corporation (NYSE: BSX) today announced that it has reached the milestone of 1000 European patients using its LATITUDE® Patient Management System. The LATITUDE system remotely monitors patients with implantable cardiac devices, gathering information on both the device and a patient’s heart health status. more...

Powell Gilbert Moves To Fleet Street
Mar 2010

IP powerhouse, Powell Gilbert LLP, has taken new premises at 85 Fleet Street after outgrowing its space in the former Patent Office at 25 Southampton Buildings in its first three years. more...

Bridge4Bio Helps Life Science Companies
Mar 2010

International business consultancy group, Bridge4Bio employs its ten-strong global consultant network to help life sciences and biotechnology companies progress their business growth plans faster, more efficiently and at a lower cost. more...

New Pharmaceutical Expert Advisory Panel
Mar 2010

The Royal Pharmaceutical Society of Great Britain (RPSGB) today announced the establishment of the Pharmaceutical Science Expert Advisory Panel to serve as the key advisory resource for the professional body on scientific strategy, leadership, advocacy, assessment and review. more...

Ipsen Grants Rhythm Worldwide License
Mar 2010

Ipsen, a global biotechnology specialty care group, and Rhythm Pharmaceuticals (Rhythm), a biotechnology company developing peptide therapeutics for metabolic diseases, announced today that they have concluded a license agreement for Ipsen’s proprietary peptide therapeutics targeting obesity, metabolic diseases, and gastrointestinal disorders. more...

Roche Purchases Microarray Assets
Mar 2010

Roche Diagnostics has purchased assets from BioMicro Systems for all products associated with the Roche NimbleGen microarray workflow. These assets consist of key instrumentation in the comprehensive Roche NimbleGen microarray workflow including the NimbleGen Hybridization Systems (both 4- and 12-bay models). more...

ACM Appoints General Manager
Mar 2010

ACM Global Central Laboratory, the global central lab that continually defines the customer-service standard with its flexible approach, today announced the newest member of its Clinical Trials team, Nandan Rao as the general manager, Asia Pacific located in Mumbai, India. Initially, Rao will have oversight of trials conducted with ACM Global’s partner lab in the region. more...

ClinTec & HCG Celebrate Partnership
Mar 2010

Dr Rabinder Buttar, PhD. President & CEO of ClinTec International and Frank S. Kilpatrick, President of Healthcare Communications Group (HCG), El Segundo, C A will celebrate their companies’ successful collaboration at the upcoming 22nd Annual Drug Information Association (DIA) EuroMeeting in Monaco on March 8-10, 2010. more...

BioLAGO Facilitates Cancer Therapy Project
Mar 2010

Hope for breast cancer patients – under the leadership of the Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), a cross border cooperation is to start between hospitals and bioanalytical laboratories of the Rhine Valley and Lake Constance region. more...

Intellicig On Top Of The Research World
Mar 2010

Leading electronic cigarette brand Intellicig has been accepted into one of the world's top centres for biomedical research.To make their products the healthiest and cleanest on the market, Intellicig has established a laboratory at Manchester’s Bioscience Incubator to perform their own clinical trials on their products. more...

New Biocitech CEO Jean-François Boussard
Mar 2010

Biocitech SAS, the Paris life science technology park, today announced that its board has appointed Jean-François Boussard as CEO with effect from April 1st. Jean-François Boussard replaces Jacques Lhomel, who is taking retirement to pursue a number of personal projects. more...

Michael J. Fox Made Honorary Doctor
Mar 2010

The renowned advocate and actor Michael J. Fox is to be made honorary doctor of medicine at Karolinska Institutet in recognition of his work raising funds and awareness for Parkinson’s disease as the founder of the Michael J. Fox Foundation for Parkinson’s Research (MJFF). more...

International NanoMicroClub Launched
Mar 2010

The Nanotechnology Knowledge Transfer Network (NanoKTN), and the Institute of Nanotechnology (IoN), has announced its collaboration that with the support of Technology Strategy Board funding, will encourage and support global business development for UK SMEs. more...

Integromics & TATAA Biocenter Collaborate
Mar 2010

Integromics S.L., the leading provider of bioinformatics solutions to gene expression researchers, has announced an exciting collaboration with the TATAA Biocenters in Sweden and the Czech Republic, to provide expert training in qPCR data analysis using RealTime StatMiner. more...

PA Consulting & ERBI Cambridge Seminar
Mar 2010

A seminar and dinner held on 26 January at Clare College Cambridge for emerging companies and their investors focusing on Adapting to life in the new economic environment – the challenge for start-ups attracted full attendance, demonstrating that venture-backed companies may be ahead in planning for the future and leading the UK out of recession. more...

Almac Expands Radiolabelling Facilities
Mar 2010

Almac, an integrated contract development and manufacturing organization supporting the international pharmaceutical and biotechnology industries, has further enhanced its radiolabelling capabilities with a significant facility expansion. more...

Hiroshi Uchida President & CEO of Magellan
Mar 2010

Magellan Biosciences, Inc., an emerging leader in
clinical diagnostics, announced that Hiroshi Uchida, Ph.D., has joined the company as president and chief
executive officer. He will also serve as a company director. Dr. Uchida (50) has more than 20 years of
leadership experience in the global medical technology and management consulting industries. more...

imaGenes Roche NimbleGen Certification
Mar 2010

Roche NimbleGen (SIX: RO, ROG; OTCQX: RHHBY) is pleased to announce that imaGenes GmbH, located in Berlin, Germany, has passed the certification process to qualify as a Roche NimbleGen Certified Service Provider (CSP) for DNA Methylation Analysis. more...
This month's featured video

GE Launches Biacore Sensor Chip CM7
Mar 2010

GE Healthcare announces the launch of Sensor Chip CM7. Designed for use with GE Healthcare’s Biacore™ systems, Sensor Chip CM7 has the high immobilization capacity required to support fragment-based screening of small molecules. more...

Thermo New Water Quality Specifications
Mar 2010

Thermo Fisher Scientific, the world leader in serving science, today announced new water quality specifications for the Thermo Scientific Nanopure Life Science water purification system. Thermo Fisher evaluated the system to see how well it cleared bacteria, pyrogens and nucleases from a sample using highly sensitive testing protocols. more...

SBS Biopharmaceuticals Symposium
20-21 May

Biopharmaceuticals is a rapidly growing sector of the pharmaceuticals industry. Join us for this two-day program, featuring top-notch sessions and keynote presentations. Poster presentations, an exhibit hall and a networking reception make this SBS Symposium a powerful resource.
more...

SBS 16th Annual Conference & Exhibition
11-15 April

More than 2,000 scientists, innovators, researchers and industry analysts will converge in Phoenix to learn about the latest trends and basic and applied research that are transforming the way new pharmaceuticals are developed. more...

Progress in the implementation of Label-Free Dectetion - part 1: cell-based assays
Fall 2008

Overall it remains unclear whether label-free will break into main stream cell-based lead discovery or will mostly fill the gaps that other technologies do less well? more...

Natural product pharmaceuticals - the third generation
By Dr Melanie McCullagh

Compounds derived from natural products have made a big impact on the pharmaceutical industry. Of the 1,010 NCEs approved between January 1981 and June 2006, 43 were unaltered natural products (NPs) and a further 232 (23%) were second generation NP derivatives1. more...

TECHNOLOGY, bane or bonanza for the pharmaceutical industry?
By Dr Stephen Naylor, Adam W. Culbertson and Dr Stephen J. Valentine

While the adoption of new technologies into the drug development process has often been seen as a panacea this article argues that, without a true understanding of the complexities how can we expect it to be the bonanza to the pharmaceutical industry and the cure for all its woes? more...

Prediction v Attraction
By Professor Malcolm Young

A substantial number of very valuable drugs have gone, or are about to go, off patent; too few good new premium drugs are coming through to market more...

Microwave-Assisted Orgainc Synthesis an Enabling Technology with Disruptive Potential.
Fall 2008

Since the original publications on the benefits of conducting organic reactions in a microwave by Gedye1 and Majetich2 in the mid-80s, the uptake of this technique was sluggish at best for the next 12-14 years. more...

High Throughput Screening, High Content Screening, Primary and Stem Cells
By Dr Richard M. Eglen

Over the past decade, the use of cell-based assays has accelerated in modern drug discovery. Indeed, the majority of assays in either target validation or lead identification/optimisation all now employ cell-based technologies. more...

Progress in the Implementation of Label-Free Detection - part 1: cell-based assays
Summer 08

Progress made in the use of impedance and optical grating technologies for label-free detection of cell-based assays where examined in HTStec’s recent Cell-Based Label-Free Detection Trends 2008 report. more...

Biologists Flirt with Models
By Gordon Webster

The enormous challenge posed by the complexity of biological systems represents a potential intellectual impasse to researchers and threatens to stall future progress in basic biology and healthcare. more...

High content screening – the next challenge: effective data mining and exploration
By Dr Kurt Zingler and Dr Stephan Heyse

The use of high content screening within HTS is growing and with many past hurdles now overcome, the need for effective tools for data analysis is becoming paramount. more...

Biomarker signal definition
By Dr Gordon F. Kapke and Dr Nigel Brown

Due to the numerous challenges in the industry, pharmaceutical companies are examining all aspects of the drug development process and rebuilding their
associated business models as necessary. more...

The Personalized Medicine Coalition
The Case for Personalized Medicine, Second Edition

The Personalized Medicine Coalition (PMC), representing a broad spectrum of academic, industrial, patient, provider, and payer communities, seeks to advance the understanding and adoption of personalized medicine concepts and products for the benefit of patients.
more...

Reshaping the landscape of cancer drug discovery and development
By Dr Paolo Paoletti

The landscape of cancer drug discovery and development is shifting – adjusting and reshaping itself in response to the huge rush of scientific knowledge more...

Human ES Cell Derived Functional Cells as Tools in Drug Discovery
By Dr Petter Björquist, Dr Peter Sartipy, Dr Raimund Strehl and Dr Johan Hyllner

The drug discovery process is extremely-time consuming and expensive. Consequently, novel approaches for these processes and for reducing late-stage attrition are of great value for the pharmaceutical industry. more...

The Microplate Market Past, Present and Future
By Dr Peter Banks

Microplates and the peripheral markets of liquid handling and detection technologies exist within almost all laboratories performing assays. This article discusses what, if any, are their growth expectations and whether there are new technologies on the horizon that could make the microplate obsolete. more...

Letting the Target Determine your Compound Acquisition Strategy
By Dr John Harris

With compound libraries likely to remain the cornerstone of hit and lead discovery for the foreseeable future, this paper seeks to summarise current and future approaches to optimal library design and compound acquisition, using examples and experimental evidence of the success, limitations and weaknesses of target-led approaches in comparison with diversity-screening alternatives. more...

Removal of Contaminating Genomic DNA in QRT-PCR using a Shrimp Nuclease
Nicky Quipse, Saima Naveed Nayab and Ian Kavanagh

DNA contamination can often occur in quantitative reverse transcription – polymerase chain reactions (QRT-PCR), and should be removed in order to avoid false positive results. more...

The Effect of Amplicon Charcteristics on the success of Fast QPCR
Gerwyn Jones, Sryana Kapavaparu, Saima Nayab and Ian Kavanagh

Employing fast QPCR cycling protocols is a simple and effective way of maximising throughput by reducing run durations. Fast cycling protocols can easily be achieved by reducing the temperature step dwell times. more...

SEARCH