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The Microplate Market Past, Present and Future
By Dr Peter Banks
Microplates and the peripheral markets of liquid handling and detection technologies exist within almost all laboratories performing assays. This article discusses what, if any, are their growth expectations and whether there are new technologies on the horizon that could make the microplate obsolete.
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Letting the Target Determine your Compound Acquisition Strategy
By Dr John Harris
With compound libraries likely to remain the cornerstone of hit and lead discovery for the foreseeable future, this paper seeks to summarise current and future approaches to optimal library design and compound acquisition, using examples and experimental evidence of the success, limitations and weaknesses of target-led approaches in comparison with diversity-screening alternatives.
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Monochromator vs Filter-based Plate Readers; horses for courses, or a winning combination?
By Dr John Comley
This article is based around feedback obtained in HTStec’s recent Multi-Mode Microplate Reader Trends 2007 Report.
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qPCR Assays; end user practices and latest vendor offerings
By Dr John Comley
This review provides an insight into real-time quantitative PCR (qPCR) assays today.
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Of Mice and Men
By Dr Catherine A. Brady
The effort to develop drugs that interact with the human immune system (whether by accident or design) has been dogged by a mismatch between the data derived from animal models (mice in particular) and that found in man.
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Emerging Real-time PCR applications
Dr Mikael Kubista
Since its introduction on the commercial market little more than 10 years ago, real-time PCR has become the main technical platform for nucleic aciddetection in research and development, as well as in routine diagnostics. more...
21st century VACCINES a Development Renaissance
By Dr Jeff Stoddard, Charles Drucker and Dr Nigel Brown
Human beings have benefited from vaccines for more than two centuries. From eradicating some of the deadliest diseases to nearly eliminating a host of others, including polio, measles, mumps and tetanus – vaccines are one of the world’s greatest lifesavers.
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Trends in the microRNA Marketplace
By Kathy Gray and Dr Enal Razvi
In this article, a recent market analysis is discussed aimed at understanding the market landscape, trends and opportunity in the rapidly-expanding microRNA marketplace. These market analyses are presented in detail in a recently published MicroRNA 2008 market report.
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Next Generation DNA Sequencing Technologies
By Dr Bruce E. Taillon and Brendon Hill
Human genetics is the foundation of disease as well as the response to pharmaceutical agents. Today, promising drugs are abandoned due to the lack of significant efficacy in broad patient populations. Recently, blockbuster drugs have been removed from the market due to unexplained toxicity not revealed in clinical trials.
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A Focus on Molecular Imaging
By Dr Ken Rubenstein
By combining cutting-edge biomedical research with the time-proven ability to visualise the unseen, the rapidly emerging field of molecular imaging promises to open new vistas for a wide range of individuals, from basic researchers to scientists working in drug discovery and development and to physicians in medical practice.
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The importance of liquid handling quality assurance through the drug discovery process
By Dr Nathaniel G Hentz
The tug-of-war between quality and productivity is an issue facing all drug discovery companies, competing in a fierce race to bring breakthrough drugs to market before the competition.
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NOVARTIS VACCINES leading through innovation and technology
By Dr Joerg Reinhardt
Every year, vaccines save millions of lives by preventing major human diseases, protecting individuals and those close to them, and offering widespread public defence against disease.
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